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PDE10A inhibitor 3e

Chemical Structure : PDE10A inhibitor 3e

CAS No.: 2413984-22-0

PDE10A inhibitor 3e

Catalog No.: PC-25003Not For Human Use, Lab Use Only.

PDE10A inhibitor 3e is a potent, selective phosphodiesterase 10A (PDE10A) inhibitor with IC50 of 6.5 nM, >95-fold selective over other PDEs.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PDE10A inhibitor 3e is a potent, selective phosphodiesterase 10A (PDE10A) inhibitor with IC50 of 6.5 nM, >95-fold selective over other PDEs.

Physicochemical Properties

M.Wt 416.84
Formula C24H14ClFN2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-3-(2-(5-Chloro-1-phenyl-1H-benzo[d]imidazol-2-yl)vinyl)-6-fluoro-4H-chromen-4-one

References

1. Yan-Fa Yu, et al. ACS Chem Neurosci. 2020 Apr 1;11(7):1058-1071.

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