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PDE11A4 inhibitor 14b

Chemical Structure : PDE11A4 inhibitor 14b

CAS No.:

PDE11A4 inhibitor 14b

Catalog No.: PC-23191Not For Human Use, Lab Use Only.

PDE11A4 inhibitor 14b is a potent, selective PDE11A4 inhibitor with IC50 of 53 nM, cAMP EC50 of 4.3 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PDE11A4 inhibitor 14b is a potent, selective PDE11A4 inhibitor with IC50 of 53 nM, cAMP EC50 of 4.3 uM.

Physicochemical Properties

M.Wt 391.43
Formula C19H14FN7S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(1-(4-fluorophenyl)-3-methyl-6-(1-methyl-1H-pyrazol-5-yl)-1H-pyrazolo[3,4-b]pyridin-4-yl)-1,3,4-thiadiazole

References

1. Mahmood SU, et al. J Med Chem. 2024 Sep 25. doi: 10.1021/acs.jmedchem.4c01794.

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