SMQ-02-57 (PDE11A4 inhibitor 23b) | PDE11A4 inhibitor

Chemical Structure : PDE11A4 inhibitor 23b

Catalog No.: PC-21270Not For Human Use, Lab Use Only.

SMQ-02-57 (PDE11A4 inhibitor 23b) is a potent, selective PDE11A4 inhibitor with IC50 of 12 nM.

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Biological Activity

SMQ-02-57 (PDE11A4 inhibitor 23b) is a potent, selective PDE11A4 inhibitor with IC50 of 12 nM.

M.Wt	424.46
Formula	C22H22F2N6O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(difluoromethyl)-N,N-diethyl-6-(1-methyl-1H-pyrazol-5-yl)-1-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxamide

1. Mahmood SU, et al. J Med Chem. 2023 Nov 9;66(21):14597-14608.
2. E Amurrio, et al. bioRxiv [Preprint]. 2025 May 21:2025.05.20.654583.