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Chemical Structure : PDE2 inhibitor 4
Catalog No.: PC-35839Not For Human Use, Lab Use Only.
PDE2 inhibitor 4 is a potent, selective, orally available inhibitor of PDE2 with IC50 of 2 nM, displays high selectivity versus other PDE isoforms.
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PDE2 inhibitor 4 is a potent, selective, orally available inhibitor of PDE2 with IC50 of 2 nM, displays high selectivity versus other PDE isoforms.
PDE2 inhibitor 4 exhibits excellent pharmacokinetic properties in multiple species and improves cognitive performance in both the rat Novel Object Recognition and rhesus Object Recognition assays.
| M.Wt | 352.317 | |
| Formula | C16H15F3N4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Stachel SJ, et al. ACS Med Chem Lett. 2018 Jul 26;9(8):815-820.
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