PDE3B inhibitor 18f | PDE3B inhibitor | Probechem Biochemicals

Chemical Structure : PDE3B inhibitor 18f

Catalog No.: PC-25899Not For Human Use, Lab Use Only.

PDE3B inhibitor 18f (PDE3B-IN-3) is a potent, subtype selective PDE3B inhibitor with IC50 of 4.5 nM, >30-fold selective over PDE3A (IC50=150 nM).

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Biological Activity

PDE3B inhibitor 18f (PDE3B-IN-3) is a potent, subtype selective PDE3B inhibitor with IC50 of 4.5 nM, >30-fold selective over PDE3A (IC50=150 nM).

M.Wt	450.47
Formula	C24H23FN4O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(2-fluoro-4-((2-(3-nitrobenzyl)-3-oxocyclohex-1-en-1-yl)amino)phenyl)-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one

1. Edmondson SD, et al. Bioorg Med Chem Lett. 2003 Nov 17;13(22):3983-7.