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PDE4B inhibitor A-33

Chemical Structure : PDE4B inhibitor A-33

CAS No.: 915082-52-9

PDE4B inhibitor A-33

Catalog No.: PC-21517Not For Human Use, Lab Use Only.

PDE4B inhibitor A-33 is a potent, selective inhibitor of PDE4B with IC50 of 15 nM, >100-fold selective over PDE4D.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

PDE4B inhibitor A-33 is a potent, selective inhibitor of PDE4B with IC50 of 15 nM, >100-fold selective over PDE4D.

Physicochemical Properties

M.Wt 387.88
Formula C19H18ClN3O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-[[2-(5-Chloro-2-thienyl)-5-ethyl-6-methyl-4-pyrimidinyl]amino]benzeneacetic acid

References

1. Kenji Naganuma, et al. Bioorg Med Chem Lett. 2009 Jun 15;19(12):3174-6.

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