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Chemical Structure : PDE5-IN-6c
Catalog No.: PC-60093Not For Human Use, Lab Use Only.
A novel potent, selective PDE5 inhibitor with IC50 of 0.056 nM for PDE5A1.
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A novel potent, selective PDE5 inhibitor with IC50 of 0.056 nM for PDE5A1; displays >500-fold selectivity over PDE6; exhibits good efficacy in mouse model of Alzheimer's disease.
| M.Wt | 420.897 | |
| Formula | C23H21ClN4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Fiorito J, et al. J Med Chem. 2017 Nov 9;60(21):8858-8875.
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