PDE7A inhibitor 26

You are here:Home-Chemical Inhibitors & Agonists-Metabolic Enzyme/Protease-Phosphodiesterase (PDE)-PDE7A inhibitor 26

Chemical Structure : PDE7A inhibitor 26

Catalog No.: PC-23896Not For Human Use, Lab Use Only.

PDE7A inhibitor 26 is a potent, selective PDE7A inhibitor with IC50 of 3.7 nM, 54-fold selective over PDE7B.

Packing	Price	Stock	Quantity
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PDE7A inhibitor 26 is a potent, selective PDE7A inhibitor with IC50 of 3.7 nM, 54-fold selective over PDE7B.
PDE7A inhibitor 26 weakly inhibits PDE4D with IC50 of 1.6 uM.
PDE7A inhibitor 26 exhibits cell IC50 of 0.39 uM for ECR5 enhancer activity.
PDE7A inhibitor 26 is a useful probe to unveil new pharmacological roles of PDE7A-dependent signaling, as exemplified by the in vivo antiosteoporotic effects.

Physicochemical Properties

M.Wt	463.97
Formula	C25H26ClN5O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-5-chloro-6-cyclopropyl-3-ethyl-2-((1-(5-phenylpicolinoyl)pyrrolidin-3-yl)amino)pyrimidin-4(3H)-one

References

1. Kondo K, et al. ACS Med Chem Lett. 2024 Dec 27;16(1):167-173.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com