PDE8A inhibitor 3a

Chemical Structure : PDE8A inhibitor 3a

Catalog No.: PC-23487Not For Human Use, Lab Use Only.

PDE8A inhibitor 3a is a potent, selective phosphodiesterase 8A (PDE8A) inhibitor with IC50 of 10 nM, >220-fold selective over PDE1B, PDE3A, PDE5A1, PDE7A1, PDE9A2, and PDE11A4.

Packing	Price	Stock	Quantity
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

PDE8A inhibitor 3a is a potent, selective phosphodiesterase 8A (PDE8A) inhibitor with IC50 of 10 nM, >220-fold selective over PDE1B, PDE3A, PDE5A1, PDE7A1, PDE9A2, and PDE11A4.
PDE8A inhibitor 3a notably improved spatial learning and memory, increased the avoidance latency and decreased the error times in the UCCAO-treated mice.

Physicochemical Properties

M.Wt	354.75
Formula	C14H13ClF2N6O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-chloro-9-(1-(4-(2,2-difluoroethoxy)pyridin-2-yl)ethyl)-9H-purin-6-amine

References

1. Huang Y, et al. J Med Chem. 2020 Dec 24;63(24):15852-15863.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com