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Chemical Structure : PDHPS1
Catalog No.: PC-49184Not For Human Use, Lab Use Only.
PDHPS1 is an endogenous stable peptide which is derived from the C-terminal (2090-2110) of NUMA1, inhibits the proliferation of ovarian cancer cells in vitro, regulates ovarian cancer development through targeting YAP1 signaling, binds to and interacts with protein phosphatase 2 phosphatase activator (PTPA).
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PDHPS1 is an endogenous stable peptide which is derived from the C-terminal (2090-2110) of NUMA1, inhibits the proliferation of ovarian cancer cells in vitro, regulates ovarian cancer development through targeting YAP1 signaling, binds to and interacts with protein phosphatase 2 phosphatase activator (PTPA).
PDHPS1 has no obvious adverse effects on ovarian epithelium and hepatorenal function.
PDHPS1 (10 mmol/L/kg, i.p.) inhibits ovarian tumor growth in xenograft tumors models.
| M.Wt | ||
| Formula | ||
| Appearance | Solid | |
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| Solubility |
10 mM in DMSO |
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1. Xinxing Pan, et al. Mol Cancer Ther. 2022 Jul 5;21(7):1160-1170.
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