PDHPS1

Chemical Structure : PDHPS1

Catalog No.: PC-49184Not For Human Use, Lab Use Only.

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Biological Activity

PDHPS1 is an endogenous stable peptide which is derived from the C-terminal (2090-2110) of NUMA1, inhibits the proliferation of ovarian cancer cells in vitro, regulates ovarian cancer development through targeting YAP1 signaling, binds to and interacts with protein phosphatase 2 phosphatase activator (PTPA).
PDHPS1 has no obvious adverse effects on ovarian epithelium and hepatorenal function.
PDHPS1 (10 mmol/L/kg, i.p.) inhibits ovarian tumor growth in xenograft tumors models.

Physicochemical Properties

M.Wt
Formula
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	IATTTASAATAAAIGATPRAK

References

1. Xinxing Pan, et al. Mol Cancer Ther. 2022 Jul 5;21(7):1160-1170.

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PDHPS1

Biological Activity

Physicochemical Properties

References

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