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PF-00610355

Chemical Structure : PF-00610355

CAS No.: 862541-45-5

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PF-00610355 (PF-610355)

Catalog No.: PC-61871Not For Human Use, Lab Use Only.

PF-00610355 (PF 610355) is a potent, selective, and long-acting β2-adrenoreceptor agonist with EC50 of 0.26 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    PF-00610355 (PF 610355) is a potent, selective, and long-acting β2-adrenoreceptor agonist with EC50 of 0.26 nM.
    PF-00610355 displays 220-fold selectivity over β1.
    PF-00610355 exhibits potential as inhaled ultra-long-acting bronchodilators for the treatment of asthma and chronic obstructive pulmonary disease.

    Physicochemical Properties

    M.Wt 617.76
    Formula C34H39N3O6S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-((4'-hydroxy(1,1'-biphenyl)-3-yl)methyl)-3-(2-(((2R)-2-hydroxy-2-(4-hydroxy-3-((methylsulfonyl)amino)phenyl)ethyl)amino)-2-methylpropyl)-benzeneacetamide

    References

    1. Glossop PA, et al. J Med Chem. 2010 Sep 23;53(18):6640-52.

    2. Diderichsen PM, et al. Br J Clin Pharmacol. 2013 Nov;76(5):752-62.

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