PF-03715455 | p38α inhibitor | Probechem Biochemicals

You are here:Home-Chemical Inhibitors & Agonists-Ras-Raf-MAPK-ERK Pathway-p38 MAPK-PF-03715455

Chemical Structure : PF-03715455

PF-03715455 (PF03715455)

Catalog No.: PC-63103Not For Human Use, Lab Use Only.

PF-03715455 is a highly potent and selective inhibitor for p38α MAPK with IC50 of 1.6 nM.

Packing	Price	Stock	Quantity
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

PF-03715455 is a highly potent and selective inhibitor for p38α MAPK with IC50 of 1.6 nM.
PF-03715455 shows efficacy and safety profiles as an inhaled agent for the treatment of COPD.

Physicochemical Properties

M.Wt	700.273
Formula	C35H34ClN7O3S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(3-(tert-butyl)-1-(3-chloro-4-hydroxyphenyl)-1H-pyrazol-5-yl)-3-(2-((3-(2-((2-hydroxyethyl)thio)phenyl)-[1,2,4]triazolo[4,3-a]pyridin-6-yl)thio)benzyl)urea

References

1. Millan DS, et al. J Med Chem. 2011 Nov 24;54(22):7797-814.

2. Singh D, et al. Eur J Clin Pharmacol. 2015 Oct;71(10):1175-84.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

PF-03715455 (PF03715455)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.