Chemical Structure : PF-04191834
CAS No.:
1029317-21-2
PF-04191834
(PF-4191834)
Catalog No. : PC-61882Not For Human Use, Lab Use Only.
PF-04191834 (PF-4191834) is a potent, non‐iron chelating, non‐redox, selective and competitive inhibitor of 5-lipoxygenase (5-LO) with Ki of 10 nM.
Packing Price Stock Quantity 5 mg $58 In stock 0 1 2 3 4 5 10 mg $88 In stock 0 1 2 3 4 5 25 mg $148 In stock 0 1 2 3 4 5 50 mg $228 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6188201
Biological Activity
PF-04191834 (PF-4191834) is a potent, non‐iron chelating, non‐redox, selective and competitive inhibitor of 5-lipoxygenase (5-LO) with Ki of 10 nM.
Physicochemical Properties
M.Wt
393.502
Formula
C22H23N3O2S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
4-(3-((4-(1-methyl-1H-pyrazol-5-yl)phenyl)thio)phenyl)tetrahydro-2H-pyran-4-carboxamide
References
1. Masferrer JL, et al. J Pharmacol Exp Ther. 2010 Jul;334(1):294-301.
2. Rzodkiewicz P, et al. Reumatologia. 2016;54(4):161-164. Epub 2016 Oct 5.
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