PF-04677490 |CAS:1628342-10-8 Probechem Biochemicals

Chemical Structure : PF-04677490

PF-04677490 (PF04677490)

Catalog No.: PC-63526Not For Human Use, Lab Use Only.

PF-04677490 is a potent, selective PDE1 inhibitor with IC50 of 21 nM for PDE1B.

Packing	Price	Stock	Quantity
25 mg		Get quote
100 mg		Get quote
200 mg		Get quote
1 g		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

PF-04677490 is a potent, selective PDE1 inhibitor with IC50 of 21 nM for PDE1B.
PF-04677490 efficaciously inhibits cAMP- and cGMP-hydrolytic activity in preparations from human myocardium at concentrations selective for PDE1.

Physicochemical Properties

M.Wt	327.388
Formula	C17H21N5O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	7,8-dimethoxy-N-(1-(5-methyl-1H-pyrazol-3-yl)propan-2-yl)quinazolin-4-amine

References

1. Humphrey JM, et al. J Med Chem. 2018 May 10. doi: 10.1021/acs.jmedchem.8b00374.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

PF-04677490 (PF04677490)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.