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PF-04701475

Chemical Structure : PF-04701475

CAS No.: 1488407-52-8

PF-04701475 (PF04701475)

Catalog No.: PC-61705Not For Human Use, Lab Use Only.

PF-04701475 is a potent positive allosteric modulator of AMPA receptor with EC50 of 123 nM, a prototype used to explore AMPAR-mediated pharmacology in vivo.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    PF-04701475 is a potent positive allosteric modulator of AMPA receptor with EC50 of 123 nM, a prototype used to explore AMPAR-mediated pharmacology in vivo.

    Physicochemical Properties

    M.Wt 369.45
    Formula C17H24FN3O3S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-[[(5S)-3-[3-Fluoro-4-(1-pyrrolidinyl)phenyl]-4,5-dihydro-5-isoxazolyl]methyl]-2-propanesulfonamide

    References

    1. Patel NC, et al. J Med Chem. 2013 Nov 27;56(22):9180-91.

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