PF-04701475 | AMPAR PAM | Probechem Biochemicals

Chemical Structure : PF-04701475

PF-04701475 (PF04701475)

Catalog No.: PC-61705Not For Human Use, Lab Use Only.

PF-04701475 is a potent positive allosteric modulator of AMPA receptor with EC50 of 123 nM, a prototype used to explore AMPAR-mediated pharmacology in vivo.

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Biological Activity

PF-04701475 is a potent positive allosteric modulator of AMPA receptor with EC50 of 123 nM, a prototype used to explore AMPAR-mediated pharmacology in vivo.

Physicochemical Properties

M.Wt	369.45
Formula	C17H24FN3O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-[[(5S)-3-[3-Fluoro-4-(1-pyrrolidinyl)phenyl]-4,5-dihydro-5-isoxazolyl]methyl]-2-propanesulfonamide

References

1. Patel NC, et al. J Med Chem. 2013 Nov 27;56(22):9180-91.

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PF-04701475 (PF04701475)

Biological Activity

Physicochemical Properties

References

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