PF-04937319 | Glucokinase activator | Probechem Biochemicals

Chemical Structure : PF-04937319

CAS No.: 1245603-92-2

PF-04937319 (Nerigliatin, PF 4937319, PB-201)

Catalog No.: PC-49835Not For Human Use, Lab Use Only.

PF-04937319 (Nerigliatin, PB-201, PF 4937319) is a partial, pancreas/liver-dual glucokinase activator with EC50 of 174 nM, induces glucose metabolism and reduces glucose levels for the treatment of type 2 diabetes.

Packing	Price	Stock
10 mg	$158	In stock
25 mg	$258	In stock
50 mg	$398	In stock
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Biological Activity

PF-04937319 (Nerigliatin, PB-201, PF 4937319) is a partial, pancreas/liver-dual glucokinase activator with EC50 of 174 nM, induces glucose metabolism and reduces glucose levels for the treatment of type 2 diabetes.

Physicochemical Properties

M.Wt	432.44
Formula	C22H20N6O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N,N-dimethyl-5-((2-methyl-6-((5-methylpyrazin-2-yl)carbamoyl)benzofuran-4-yl)oxy)pyrimidine-2-carboxamide

References

1. Amin NB, et al. Diabetes Obes Metab. 2015 Aug;17(8):751-9.

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PF-04937319 (Nerigliatin, PF 4937319, PB-201)

Biological Activity

Physicochemical Properties

References

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