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PF-04937319

Chemical Structure : PF-04937319

CAS No.: 1245603-92-2

PF-04937319 (PF 4937319, PB-201)

Catalog No.: PC-49835Not For Human Use, Lab Use Only.

PF-04937319 (PB-201, PF 4937319) is a partial, pancreas/liver-dual glucokinase activator with EC50 of 174 nM, induces glucose metabolism and reduces glucose levels for the treatment of type 2 diabetes.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

PF-04937319 (PB-201, PF 4937319) is a partial, pancreas/liver-dual glucokinase activator with EC50 of 174 nM, induces glucose metabolism and reduces glucose levels for the treatment of type 2 diabetes.

Physicochemical Properties

M.Wt 432.44
Formula C22H20N6O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N,N-dimethyl-5-((2-methyl-6-((5-methylpyrazin-2-yl)carbamoyl)benzofuran-4-yl)oxy)pyrimidine-2-carboxamide

References

1. Amin NB, et al. Diabetes Obes Metab. 2015 Aug;17(8):751-9.

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