Chemical Structure : PF-04991532
CAS No.:
1215197-37-7
PF-04991532
(PF4991532, PF 04991532)
Catalog No. : PC-61880Not For Human Use, Lab Use Only.
PF-04991532 (PF4991532) is a potent, hepatoselective Glucokinase (GK) activator with EC50 of 90±45 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6188001
Biological Activity
PF-04991532 (PF4991532) is a potent, hepatoselective Glucokinase (GK) activator with EC50 of 90±45 nM.
Physicochemical Properties
M.Wt
396.37
Formula
C18H19F3N4O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
(S)-6-(3-Cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid
References
1. Pfefferkorn JA, et al. J Med Chem
2. Erion DM, et al. PLoS One
3. Ghosh A, et al. Drug Metab Dispos
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