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PF-05241328

Chemical Structure : PF-05241328

CAS No.: 1387633-03-5

PF-05241328 (PF05241328;PF 5241328)

Catalog No.: PC-61857Not For Human Use, Lab Use Only.

PF-05241328 (PF 5241328) is a potent and selective, orally active inhibitor of voltage-dependent sodium channel Nav1.7 with IC50 of 31 nM.

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Biological Activity

PF-05241328 (PF 5241328) is a potent and selective, orally active inhibitor of voltage-dependent sodium channel Nav1.7 with IC50 of 31 nM.

Physicochemical Properties

M.Wt 436.911
Formula C19H21ClN4O4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(5-Chloro-6-(2-methylpropoxy)-3-pyridinyl)-3-methyl-N-(methylsulfonyl)-1H-indazole-5-carboxamide

References

1. Jones HM, et al. Clin Pharmacokinet. 2016 Jul;55(7):875-87.

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