Chemical Structure : PF-05381941
Catalog No.: PC-61199Not For Human Use, Lab Use Only.
PF-05381941 (PF 05381941, PF05381941) is a potent, dual TAK1/p38a inhibitor with IC50 of 156/186 nM respectively, with good kinome selectivity against 50 representative kinases.
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PF-05381941 (PF 05381941, PF05381941) is a potent, dual TAK1/p38a inhibitor with IC50 of 156/186 nM respectively, with good kinome selectivity against 50 representative kinases; inhibits LPS-stimulated release of TNF-α from human peripheral mononuclear cells with IC50 of 8 nM.
M.Wt | 466.545 | |
Formula | C27H26N6O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Kilty I, et al. Future Med Chem. 2015;7(1):23-33.
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