Chemical Structure : PF-06273340
CAS No.:
1402438-74-7
PF-06273340
(PF06273340, PF6273340)
Catalog No. : PC-61701Not For Human Use, Lab Use Only.
PF-06273340 is a potent and selective, orally bioavailable pan-Trk kinase inhibitor with IC50 of 6, 2, and 1 nM for Trk A, B and C, respectively.
Packing Price Stock Quantity 5 mg $128 In stock 0 1 2 3 4 5 10 mg $198 In stock 0 1 2 3 4 5 25 mg $348 In stock 0 1 2 3 4 5 50 mg Get quote 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
Bulk size, bulk discount!
Welcome credit card payment!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6170101
Biological Activity
PF-06273340 (PF6273340) is a potent and selective, orally bioavailable pan-Trk kinase inhibitor with IC50 of 6, 2, and 1 nM for Trk A, B and C, respectively.
Physicochemical Properties
M.Wt
479.93
Formula
C23H22ClN7O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
N-(5-(2-amino-7-(1-hydroxy-2-methylpropan-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)pyridin-3-yl)-2-(5-chloropyridin-2-yl)acetamide
References
1. Skerratt SE, et al. J Med Chem
Contact Us
sales@probechem.com
