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PF-06526290

Chemical Structure : PF-06526290

CAS No.:

PF-06526290 (PF06526290)

Catalog No.: PC-35154Not For Human Use, Lab Use Only.

PF-06526290 is a potent, selective Nav1.3 inhibitor with IC50 of 5.1 uM, interact with the Domain 4 voltage sensor domain (D4 VSD and shows no activity for Nav1.7.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    PF-06526290 is a potent, selective Nav1.3 inhibitor with IC50 of 5.1 uM, interact with the Domain 4 voltage sensor domain (D4 VSD and shows no activity for Nav1.7.

    Physicochemical Properties

    M.Wt 402.487
    Formula C18H18N4O3S2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    4-(3-benzyl-3-methylureido)-N-(thiazol-2-yl)benzenesulfonamide

    References

    1. Wang L, et al. Br J Pharmacol. 2015 Oct;172(20):4905-18.

    2. Wang L, et al. Br J Pharmacol. 2018 May 23. doi: 10.1111/bph.14338.

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