PF-06526290 | Probechem Biochemicals

Chemical Structure : PF-06526290

PF-06526290 (PF06526290)

Catalog No.: PC-35154Not For Human Use, Lab Use Only.

PF-06526290 is a potent, selective Nav1.3 inhibitor with IC50 of 5.1 uM, interact with the Domain 4 voltage sensor domain (D4 VSD and shows no activity for Nav1.7.

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Biological Activity

PF-06526290 is a potent, selective Nav1.3 inhibitor with IC50 of 5.1 uM, interact with the Domain 4 voltage sensor domain (D4 VSD and shows no activity for Nav1.7.

Physicochemical Properties

M.Wt	402.487
Formula	C18H18N4O3S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(3-benzyl-3-methylureido)-N-(thiazol-2-yl)benzenesulfonamide

References

1. Wang L, et al. Br J Pharmacol. 2015 Oct;172(20):4905-18.

2. Wang L, et al. Br J Pharmacol. 2018 May 23. doi: 10.1111/bph.14338.

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PF-06526290 (PF06526290)

Biological Activity

Physicochemical Properties

References

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