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PF-06648671

Chemical Structure : PF-06648671

CAS No.: 1587727-31-8

PF-06648671 (PF6648671)

Catalog No.: PC-61830Not For Human Use, Lab Use Only.

PF-06648671 (PF6648671) is a novel oral γ-secretase modulator, reduces Aβ42 and Aβ40, with concomitant increases in Aβ37 and Aβ38 in vitro.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    PF-06648671 (PF6648671) is a novel oral γ-secretase modulator, reduces Aβ42 and Aβ40, with concomitant increases in Aβ37 and Aβ38 in vitro.

    Physicochemical Properties

    M.Wt 538.928
    Formula C25H23ClF4N4O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2H-Pyrido[1,2-a]pyrazine-1,6-dione, 2-[(1S)-1-[(2S,5R)-5-[4-chloro-5-fluoro-2-(trifluoromethyl)phenyl]tetrahydro-2-furanyl]ethyl]-3,4-dihydro-7-(4-methyl-1H-imidazol-1-yl)-

    References

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