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Chemical Structure : PF-06649298
CAS No.: 1854061-16-7
Catalog No.: PC-60604Not For Human Use, Lab Use Only.
PF-06649298 (PF06649298) is a potent, selective inhibitor of the Na+/citrate transporter NaCT (SLC13A5) that shows inhibition of citrate uptake in the HEKNaCT cells with IC50 of 0.41 uM.
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|---|---|---|---|
| 5 mg | $388 | In stock | |
| 10 mg | $588 | In stock | |
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| 50 mg | Get quote | ||
| 100 mg | Get quote |
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PF-06649298 (PF06649298) potent, selective inhibitor of the Na+/citrate transporter NaCT (SLC13A5) that shows inhibition of citrate uptake in the HEKNaCT cells with IC50 of 0.41 uM.
PF-06649298 displays >60-fold selectvity over NaDC1 and NaDC3.
| M.Wt | 294.347 | |
| Formula | C16H22O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(R)-2-(4-(tert-butyl)phenethyl)-2-hydroxysuccinic acid |
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1. Pajor AM, et al. Mol Pharmacol. 2016 Dec;90(6):755-765.
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