You are here:Home-Chemical Inhibitors & Agonists-Membrane Transporter/Ion Channel-Sodium-coupled Citrate Transporter (NaCT,SLC13A5)-PF-06649298
PF-06649298

Chemical Structure : PF-06649298

CAS No.: 1854061-16-7

PF-06649298 (PF 06649298, PF06649298)

Catalog No.: PC-60604Not For Human Use, Lab Use Only.

PF-06649298 (PF06649298) is a potent, selective inhibitor of the Na+/citrate transporter NaCT (SLC13A5) that shows inhibition of citrate uptake in the HEKNaCT cells with IC50 of 0.41 uM.

Packing Price Stock Quantity
5 mg $388 In stock
10 mg $588 In stock
25 mg Get quote
50 mg Get quote
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

PF-06649298 (PF06649298) potent, selective inhibitor of the Na+/citrate transporter NaCT (SLC13A5) that shows inhibition of citrate uptake in the HEKNaCT cells with IC50 of 0.41 uM.
PF-06649298 displays >60-fold selectvity over NaDC1 and NaDC3.

Physicochemical Properties

M.Wt 294.347
Formula C16H22O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-2-(4-(tert-butyl)phenethyl)-2-hydroxysuccinic acid

References

1. Pajor AM, et al. Mol Pharmacol. 2016 Dec;90(6):755-765.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: