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Chemical Structure : PF-06815189
Catalog No.: PC-62528Not For Human Use, Lab Use Only.
PF-06815189 is a potent, selective phosphodiesterase 2 (PDE2) inhibitor with IC50 of 0.4 nM, >1,000-fold selectivity over PDE5.
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PF-06815189 is a potent, selective phosphodiesterase 2 (PDE2) inhibitor with IC50 of 0.4 nM, >1,000-fold selectivity over PDE5.
PF-06815189 also demonstrates no significant activities (EC50 >10 μM) in a broad spectrum BioPrint panel.
PF-06815189 possesses favorable pharmacological and in vitro ADME profile, the pharmacokinetic attributes.
| M.Wt | 418.38 | |
| Formula | C19H17F3N6O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Stepan AF, et al. ACS Med Chem Lett. 2018 Jan 4;9(2):68-72.
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