PF-07038124 | PDE4 inhibitor | Probechem Biochemicals

Chemical Structure : PF-07038124

PF-07038124 (PF 07038124)

Catalog No.: PC-20682Not For Human Use, Lab Use Only.

PF-07038124 (PF 07038124) is a highly potent, selective PDE4 inhibitor with IC50 of 0.5 nM for PDE4B2 in SPA assays, inhibits cytokines release of IL-4, IL-13 and IFNy from human PBMCs stimulated with PHA-L with IC50 of 135, 4.1, and 1.06 nM, respectively.

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Biological Activity

Physicochemical Properties

M.Wt	327.19
Formula	C18H22BNO4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	CCCOC1=C(OC)C=CC(C2=CN=CC([C@@]3([H])CB(OC3)O)=C2)=C1

References

1. Patent WO2020070651A1 (Example 4).

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PF-07038124 (PF 07038124)

Biological Activity

Physicochemical Properties

References

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