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PF-3635659

Chemical Structure : PF-3635659

CAS No.: 931409-24-4

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PF-3635659 (PF-03635659)

Catalog No.: PC-61894Not For Human Use, Lab Use Only.

PF-3635659 (PF-03635659) is a potent, very long dissociative half-life (slow off-rate, >1440 min) muscarinic M3 antagonist with Ki of 0.2 nM, shows potential for the treatment of chronic obstructive pulmonary disease (COPD).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    PF-3635659 (PF-03635659) is a potent, very long dissociative half-life (slow off-rate, >1440 min) muscarinic M3 antagonist with Ki of 0.2 nM, shows potential for the treatment of chronic obstructive pulmonary disease (COPD).

    Physicochemical Properties

    M.Wt 444.58
    Formula C28H32N2O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    3-(3-hydroxyphenoxy)-delta,delta-dimethyl-alpha,alpha-diphenyl-1-azetidinepentanamide

    References

    1. Glossop PA, et al. J Med Chem. 2011 Oct 13;54(19):6888-904.

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