Chemical Structure : PF-573228
CAS No.:
869288-64-2
PF-573228
(PF573228;PF 573228)
Catalog No. : PC-42602Not For Human Use, Lab Use Only.
PF-573228 is a potent, selective, ATP-competitive FAK inhibitor with IC50 of 4 nM.
Packing Price Stock Quantity 5 mg (Free Sample) $18 In stock 0 1 2 3 4 5 10 mg $98 In stock 0 1 2 3 4 5 25 mg $148 In stock 0 1 2 3 4 5 50 mg $258 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4260201
Biological Activity
PF-573228 is a potent, selective, ATP-competitive FAK inhibitor with IC50 of 4 nM.
Physicochemical Properties
M.Wt
491.4861
Formula
C22H20F3N5O3S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 51 mg/mL
Chemical Name/SMILES
2(1H)-Quinolinone, 3,4-dihydro-6-[[4-[[[3-(methylsulfonyl)phenyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-
References
1. Slack-Davis JK, et al. J Biol Chem
2. Jones ML, et al. Biochem Biophys Res Commun
3. Hiscox S, et al. Breast Cancer Res Treat
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