Catalog No.: PC-35187Not For Human Use, Lab Use Only.
PF-6683324 (PF6683324) is a potent and selective Type II PTK6/Brk inhibitor with IC50 of 76 nM in biochemical assays, also is a potent pan-TRK inhibitor.
PF-6683324 (PF6683324) is a potent and selective Type II PTK6/Brk inhibitor with IC50 of 76 nM in biochemical assays, also is a potent pan-TRK inhibitor.
PF-6683324 inhibits PTK6 phosphorylation at Y342 in engineered HET293T cells overexpressing PTK6 WT with IC50 of 0.7 uM.
PF-6683324 demonstrates superior kinase selectivity compared to the Type I inhibitors.
