PF-G23 | Cbl-b inhibitor | Probechem Biochemicals

Chemical Structure : PF-G23

PF-G23 (CBL-B inhibitor G23)

Catalog No.: PC-25779Not For Human Use, Lab Use Only.

PF-G23 (CBL-B inhibitor G23) is a potent, selective, small molecule inhibitor of E3 ligase Casitas B-lineage lymphoma proto oncogene B (CBL-B), shows binding selectivity over C-CBL.

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Biological Activity

PF-G23 (CBL-B inhibitor G23) is a potent, selective, small molecule inhibitor of E3 ligase Casitas B-lineage lymphoma proto oncogene B (CBL-B), shows binding selectivity over C-CBL.

Physicochemical Properties

M.Wt	503.05
Formula	C28H31ClN6O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-chloro-6-(3-(5-(4-methyl-4H-1,2,4-triazol-3-yl)spiro[2.3]hexan-5-yl)phenyl)-2-(((1-methylcyclobutyl)amino)methyl)-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one

References

1. Patent WO2024105563 A1, Compound G23.

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PF-G23 (CBL-B inhibitor G23)

Biological Activity

Physicochemical Properties

References

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