Chemical Structure : PF670462 dihydrochloride
CAS No.:
950912-80-8
PF670462 dihydrochloride
Catalog No. : PC-23901Not For Human Use, Lab Use Only.
PF-670462 dihydrochloride (PF670462) is a potent and selective inhibitor casein kinase CK1ε and CK1δ with IC50 of 7.7 nM and 14 nM, respectively.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-2390101
Biological Activity
PF-670462 dihydrochloride (PF670462) is a potent and selective inhibitor casein kinase CK1ε and CK1δ with IC50 of 7.7 nM and 14 nM, respectively.
Physicochemical Properties
M.Wt
410.32
Formula
C19H22Cl2FN5
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
4-(1-Cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl)pyrimidin-2-amine dihydrochloride
References
1. Badura L, et al. J Pharmacol Exp Ther. 2007 Aug;322(2):730-8.
2. Bryant CD, et al. Psychopharmacology (Berl). 2009 May;203(4):703-11.
3. Walton KM, et al. J Pharmacol Exp Ther. 2009 Aug;330(2):430-9.
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