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PFI-E3H1

Chemical Structure : PFI-E3H1

CAS No.: 2910887-73-7

PFI-E3H1

Catalog No.: PC-22418Not For Human Use, Lab Use Only.

PFI-E3H1 is a potent, selective chemical handle of Gid4 subunit of the human E3 ligase CTLH degradation complex with IC50 of 2.5 uM in NanoBRET assay measuring the Gid4/MPGLWKS interaction.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PFI-E3H1 is a potent, selective chemical handle of Gid4 subunit of the human E3 ligase CTLH degradation complex with IC50 of 2.5 uM in NanoBRET assay measuring the Gid4/MPGLWKS interaction.

Physicochemical Properties

M.Wt 362.48
Formula C22H26N4O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Acetamide, N-[cis-4-(1H-benzimidazol-2-yl)cyclohexyl]-2-[[(1R)-1-phenylethyl]amino]-

References

1. Yazdi AK, et al. RSC Med Chem. 2024 Mar 5;15(3):1066-1071.

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