PFI-E3H1

Chemical Structure : PFI-E3H1

Catalog No.: PC-22418Not For Human Use, Lab Use Only.

PFI-E3H1 is a potent, selective chemical handle of Gid4 subunit of the human E3 ligase CTLH degradation complex with IC50 of 2.5 uM in NanoBRET assay measuring the Gid4/MPGLWKS interaction.

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Biological Activity

PFI-E3H1 is a potent, selective chemical handle of Gid4 subunit of the human E3 ligase CTLH degradation complex with IC50 of 2.5 uM in NanoBRET assay measuring the Gid4/MPGLWKS interaction.

Physicochemical Properties

M.Wt	362.48
Formula	C22H26N4O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Acetamide, N-[cis-4-(1H-benzimidazol-2-yl)cyclohexyl]-2-[[(1R)-1-phenylethyl]amino]-

References

1. Yazdi AK, et al. RSC Med Chem. 2024 Mar 5;15(3):1066-1071.

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PFI-E3H1

Biological Activity

Physicochemical Properties

References

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