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PFM03

Chemical Structure : PFM03

CAS No.: 1558598-48-3

PFM03

Catalog No.: PC-23728Not For Human Use, Lab Use Only.

PFM03 is a specific MRE11 endonuclease inhibitor, affects DNA double-strand break repair (DSBR) by nonhomologous end-joining (NHEJ).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PFM03 is a specific MRE11 endonuclease inhibitor, affects DNA double-strand break repair (DSBR) by nonhomologous end-joining (NHEJ).

Physicochemical Properties

M.Wt 293.40
Formula C14H15NO2S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(Z)-3-(sec-butyl)-5-(4-hydroxybenzylidene)-2-thioxothiazolidin-4-one

References

1. Shibata A, et al. Mol Cell. 2014 Jan 9;53(1):7-18.

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