Chemical Structure : PGN 9856-isopropyl ester
CAS No.: 1177429-82-1
Catalog No.: PC-35836ANot For Human Use, Lab Use Only.
PGN 9856-isopropyl ester is the isopropyl ester, which is a potent, selective prostaglandin EP2 receptor agonist with pKi of > 8.3.
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PGN 9856-isopropyl ester is the isopropyl ester, which is a potent, selective prostaglandin EP2 receptor agonist with pKi of > 8.3.
PGN 9856-isopropyl ester produced profound decreases in monkey intraocular pressure (IOP).
PGN 9856-isopropyl ester appears to possess efficacy and duration of action properties unmatched by currently prescribed anti-glaucoma agents.
M.Wt | 425.43 | |
Formula | C24H21F2NO4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
isopropyl 2-(3-(3',4-difluoro-[1,1'-biphenyl]-3-carboxamido)phenoxy)acetate |
1. Woodward DF, et al. J Ocul Pharmacol Ther. 2019 Jun;35(5):265-277.
2. Coleman RA, et al. Br J Pharmacol. 2019 Mar;176(5):687-698.
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