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PGP-4008

Chemical Structure : PGP-4008

CAS No.: 365565-02-2

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PGP-4008 (PGP4008)

Catalog No.: PC-26311Not For Human Use, Lab Use Only.

PGP-4008 is a specific inhibitor of P-glycoprotein (P-gp)-mediated multidrug resistance (MDR), potentiates the cytotoxicity of Pgp substrate drugs (vinblastine, vincristine, and paclitaxel)

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

PGP-4008 is a specific inhibitor of P-glycoprotein (P-gp)-mediated multidrug resistance (MDR), potentiates the cytotoxicity of Pgp substrate drugs (vinblastine, vincristine, and paclitaxel)

Physicochemical Properties

M.Wt 393.49
Formula C26H23N3O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(1-Benzyl-2,3-dihydro-1H-pyrrolo[2,3-b]quinolin-4-yl)-2-phenylacetamide

References

1. Lee BD, et al. Oncol Res. 2003;14(1):49-60.

2. Lee BD, et al. J Med Chem. 2004 Mar 11;47(6):1413-22.

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