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PGRMC2 activator 25

Chemical Structure : PGRMC2 activator 25

CAS No.: 2089047-53-8

PGRMC2 activator 25 (PGRMC2 ligand)

Catalog No.: PC-62694Not For Human Use, Lab Use Only.

PGRMC2 activator 25 gain-of-function ligand for PGRMC2 (progesterone receptor membrane component 2) to promote adipogenesis.

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    Biological Activity

    PGRMC2 activator 25 is a gain-of-function ligand for PGRMC2 (progesterone receptor membrane component 2) to promote adipogenesis.
    PGRMC2 activator 25 may mimic the activity or promote the nuclear transport of heme-related molecules.

    Physicochemical Properties

    M.Wt 404.514
    Formula C24H28N4O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (S)-2-(3-(3-(but-3-yn-1-yl)-3H-diazirin-3-yl)propanamido)-4-methyl-N-(naphthalen-2-yl)pentanamide

    References

    1. Parker CG, et al. Cell. 2017 Jan 26;168(3):527-541.e29.

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