Chemical Structure : PI-3065
CAS No.: 955977-50-1
Catalog No.: PC-42925Not For Human Use, Lab Use Only.
PI-3065 is a potent inhibitor of PI3K p110δ with IC50/Ki values of 5/1.5 nM respectively.
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PI-3065 is a potent inhibitor of PI3K p110δ with IC50/Ki values of 5/1.5 nM respectively.
PI-3065 exhibits less potent activity against p110α, p110β, p110γ with IC50s of 910, 600, >10000 nM.
| M.Wt | 506.638 | |
| Formula | C27H31FN6OS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: 50 mM (2.5 mg/mL) |
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| Chemical Name/SMILES |
Thieno[3,2-d]pyrimidine, 6-[[4-(cyclopropylmethyl)-1-piperazinyl]methyl]-2-(5-fluoro-1H-indol-4-yl)-4-(4-morpholinyl)- |
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1. Ali K, et al. Nature. 2014 Jun 19;510(7505):407-11.

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