PI3Kδ inhibitor 52 |CAS:1911564-39-0 Probechem Biochemicals

Chemical Structure : PI3Kδ inhibitor 52

CAS No.: 1911564-39-0

PI3Kδ inhibitor 52 (ZUN64390)

Catalog No.: PC-61127Not For Human Use, Lab Use Only.

ZUN64390 is a potent, selective, and efficacious PI3Kδ inhibitor with IC50 of 1.7 nM, >100-fold selectivitity over PI3Kγ/α/β.

Packing	Price	Stock
5 mg	$188	In stock
25 mg	$388	In stock
100 mg	$988	In stock
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Biological Activity

ZUN64390 is a potent, selective, and efficacious PI3Kδ inhibitor with IC50 of 1.7 nM, >100-fold selectivitity over PI3Kγ/α/β.
ZUN64390 shows potent activity in mouse arthritis models.

Physicochemical Properties

M.Wt	471.444
Formula	C22H20F3N7O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(4-acetyl-3,3-dimethyl-2-oxopiperazin-1-yl)-4-(4-amino-5-(trifluoromethyl)pyrrolo[2,1-f][1,2,4]triazin-7-yl)benzonitrile

References

1. Liu Q, et al. J Med Chem. 2017 Jun 22;60(12):5193-5208.

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PI3Kδ inhibitor 52 (ZUN64390)

Biological Activity

Physicochemical Properties

References

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