PI3K-C2γ inhibitor 26 | PI3K-C2γ inhibitor

Chemical Structure : PI3K-C2γ inhibitor 26

PI3K-C2γ inhibitor 26 (Freitag-26)

Catalog No.: PC-23005Not For Human Use, Lab Use Only.

PI3K-C2γ inhibitor 26 is a potent, isoform-selective inhibitor of PI3K-C2γ with IC50 of 340 nM, with no activity against class I and III PI3Ks or a panel of 60 other protein kinases.

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Biological Activity

PI3K-C2γ inhibitor 26 is a potent, isoform-selective inhibitor of PI3K-C2γ with IC50 of 340 nM, with no activity against class I and III PI3Ks or a panel of 60 other protein kinases.

Physicochemical Properties

M.Wt	401.44
Formula	C18H19N5O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-amino-N-(3-((3,5-dimethoxyphenyl)amino)pyrazin-2-yl)benzenesulfonamide

References

1. Anne Freitag, et al. J Med Chem. 2015 Jan 8;58(1):212-21.

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PI3K-C2γ inhibitor 26 (Freitag-26)

Biological Activity

Physicochemical Properties

References

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