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PIK-108

Chemical Structure : PIK-108

CAS No.: 901398-68-3

PIK-108 (PIK108, PIK 108)

Catalog No.: PC-21948Not For Human Use, Lab Use Only.

PIK-108 is a potent, selective and allosteric PI3K p110β inhibitor with IC50 of 57 nM, 45-fold selective over PI3Kα (IC50=2600 nM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

PIK-108 is a potent, selective and allosteric PI3K p110β inhibitor with IC50 of 57 nM, 45-fold selective over PI3Kα (IC50=2600 nM).

Physicochemical Properties

M.Wt 364.45
Formula C22H24N2O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

6-Methyl-2-morpholino-8-(1-(phenylamino)ethyl)-4H-chromen-4-one

References

1. Chen JS, et al. Mol Cancer Ther. 2008 Apr;7(4):841-50.

2. Hon WC, et al. Oncogene. 2012 Aug 9;31(32):3655-66.

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