PIK-294 |CAS:900185-02-6 Probechem Biochemicals

Chemical Structure : PIK-294

CAS No.: 900185-02-6

Catalog No.: PC-42518Not For Human Use, Lab Use Only.

PIK-294 is a highly potent, selective p110δ inhibitor with IC50 of 10 nM, shows 1000-, 49- and 16-fold less potent to PI3Kα/β/γ.

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Biological Activity

PIK-294 is a highly potent, selective p110δ inhibitor with IC50 of 10 nM, shows 1000-, 49- and 16-fold less potent to PI3Kα/β/γ.

M.Wt	489.5279
Formula	C28H23N7O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	DMSO: ≥ 40 mg/mL
Chemical Name/SMILES	4(3H)-Quinazolinone, 2-[[4-amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]methyl]-5-methyl-3-(2-methylphenyl)-

1. Knight ZA, et al. Cell. 2006 May 19;125(4):733-47.

2. Martin KJ, et al. PLoS One. 2015 Feb 6;10(2):e0116250.