Chemical Structure : PIK-90
CAS No.:
677338-12-4
PIK-90
(PIK90;PIK 90)
Catalog No. : PC-42844Not For Human Use, Lab Use Only.
PIK-90 is a potent DNA-PK and PI3K inhibitor that inhibits p110α, p110γ and DNA-PK with IC50s of 11, 18 and 13 nM, respectively.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4284401
Biological Activity
PIK-90 is a potent DNA-PK and PI3K inhibitor that inhibits p110α, p110γ and DNA-PK with IC50s of 11, 18 and 13 nM, respectively.
Physicochemical Properties
M.Wt
351.3593
Formula
C18H17N5O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: < 1 mg/mL
Chemical Name/SMILES
3-Pyridinecarboxamide, N-(2,3-dihydro-7,8-dimethoxyimidazo[1,2-c]quinazolin-5-yl)-
References
1. Fan QW, et al. Cancer Res.
2. Niedermeier M, et al. Blood.
3. Knight ZA, et al. Cell.
4. Cheng CK, et al. Proc Natl Acad Sci U S A.
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