PITCOIN1

Chemical Structure : PITCOIN1

Catalog No.: PC-23007Not For Human Use, Lab Use Only.

PITCOIN1 is a potent, highly selective inhibitor of class II alpha PI3K (PI3K-C2α) with IC50 of 100 nM, with no activity against class I and III PI3Ks.

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Biological Activity

PITCOIN1 is a potent, highly selective inhibitor of class II alpha PI3K (PI3K-C2α) with IC50 of 100 nM, with no activity against class I and III PI3Ks.

Physicochemical Properties

M.Wt	424.50
Formula	C19H16N6O2S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((4-Oxo-3-phenethyl-3,4-dihydropteridin-2-yl)thio)-N-(thiazol-2-yl)acetamide

References

1. Murat Kücükdisli, et al. J Med Chem. 2023 Oct 26;66(20):14278-14302.

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PITCOIN1

Biological Activity

Physicochemical Properties

References

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