Chemical Structure : PKUMDL-LC-102
CAS No.: 22431-06-7
Catalog No.: PC-24821Not For Human Use, Lab Use Only.
PKUMDL-LC-102 is a selective, allosteric small molecule GPX4 activator (150% activation at 39.2 μM), shows no activity against COX-1, COX-2, mPGES-1, 5-LOX, LTA4H, 12-LOX, and 15-LOX.
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PKUMDL-LC-102 is a selective, allosteric small molecule GPX4 activator (150% activation at 39.2 μM), shows no activity against COX-1, COX-2, mPGES-1, 5-LOX, LTA4H, 12-LOX, and 15-LOX.
M.Wt | 219.20 | |
Formula | C10H9N3O3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
2-amino-3a,8a-dihydroxy-3a,8a-dihydroindeno[1,2-d]imidazol-8(3H)-one |
1. Li C, et al. Front Pharmacol. 2018 Oct 3:9:1120.
2. Liu X, et al. J Orthop Translat. 2025 May 7;52:344-359.
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