Chemical Structure : PKUMDL-WQ-2201
CAS No.: 592474-91-4
Catalog No.: PC-72880Not For Human Use, Lab Use Only.
PKUMDL-WQ-2201 is a potent, selective, allosteric inhibitor of PHGDH, binds to allosteric site II.
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PKUMDL-WQ-2201 is a potent, selective, allosteric inhibitor of PHGDH, binds to allosteric site II.
PKUMDL-WQ-2201 inhibited the serine biosynthesis pathway in cells, exhibited substantial inhibitory effects on MDA-MB-468 xenografts.
M.Wt | 351.805 | |
Formula | C15H14ClN3O3S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
2-Chloro-4-[5-[(ethylcarbamothioylhydrazinylidene)methyl]furan-2-yl]benzoic acid |
1. Qian Wang, et al. Cell Chem Biol. 2017 Jan 19;24(1):55-65.
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