PKUMDL-WQ-2201 | PHGDH inhibitor | Probechem Biochemicals

Chemical Structure : PKUMDL-WQ-2201

CAS No.: 592474-91-4

PKUMDL-WQ-2201 (WQ-2201)

Catalog No.: PC-72880Not For Human Use, Lab Use Only.

PKUMDL-WQ-2201 is a potent, selective, allosteric inhibitor of PHGDH, binds to allosteric site II.

Packing	Price	Stock
10 mg	$128	In stock
25 mg	$218	In stock
50 mg	$358	In stock
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Biological Activity

PKUMDL-WQ-2201 is a potent, selective, allosteric inhibitor of PHGDH, binds to allosteric site II.
PKUMDL-WQ-2201 inhibited the serine biosynthesis pathway in cells, exhibited substantial inhibitory effects on MDA-MB-468 xenografts.

Physicochemical Properties

M.Wt	351.805
Formula	C15H14ClN3O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Chloro-4-[5-[(ethylcarbamothioylhydrazinylidene)methyl]furan-2-yl]benzoic acid

References

1. Qian Wang, et al. Cell Chem Biol. 2017 Jan 19;24(1):55-65.

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PKUMDL-WQ-2201 (WQ-2201)

Biological Activity

Physicochemical Properties

References

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