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Chemical Structure : PLK1-IN-14f
Catalog No.: PC-62790Not For Human Use, Lab Use Only.
PLK1-IN-14f is a potent PLK1 inhibitor, exhibits potent activity against a panel cancer cell lines with GI50 values ranging from 0.30 to 0.60 uM.
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PLK1-IN-14f is a potent PLK1 inhibitor, exhibits potent activity against a panel cancer cell lines with GI50 values ranging from 0.30 to 0.60 uM.
PLK1-IN-14f causes cell-cycle arrest at the G2/M phase and induced apoptosis by targeting CDC25C and Mcl-1 proteins in A2780 ovarian cells.
| M.Wt | 393.454 | |
| Formula | C19H23NO6S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Long Y, et al. Bioorg Med Chem Lett. 2016 Dec 1;26(23):5674-5678.
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