PNU-159682 |CAS:202350-68-3 Probechem Biochemicals

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Chemical Structure : PNU-159682

CAS No.: 202350-68-3

Catalog No.: PC-45045Not For Human Use, Lab Use Only.

A highly potent metabolite of the anthracycline nemorubicin with outstanding cytotoxicity.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A highly potent metabolite of the anthracycline nemorubicin with outstanding cytotoxicity; a topoisomerase inhibitor and ADCs cytotoxin.

M.Wt	641.6192
Formula	C32H35NO13
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[(1S,3R,4aS,9S,9aR,10aS)-octahydro-9-methoxy-1-methyl-1H-pyrano[4',3':4,5]oxazolo[2,3-c][1,4]oxazin-3-yl]oxy]-, (8S,10S)-

1. Quintieri L, et al. Clin Cancer Res. 2005 Feb 15;11(4):1608-17.

2. Yu SF, et al. Clin Cancer Res. 2015 Jul 15;21(14):3298-306.

3. Mazzini S, et al. Bioorg Med Chem. 2012 Dec 15;20(24):6979-88.