PNU-22394 hydrochloride | 5-HT2C/5-HT2A agonist

Chemical Structure : PNU-22394 hydrochloride

CAS No.: 15923-42-9

PNU-22394 hydrochloride (PNU22394)

Catalog No.: PC-27024Not For Human Use, Lab Use Only.

PNU-22394 hydrochloride is a potent agonist for 5-HT receptors with Ki of 6.1 and 10 nM, EC50 of 7.7 nM and 23 nM for 5-HT2C and 5-HT2A, respectively.

Packing	Price	Stock
5 mg	$88	In stock
10 mg	$128	In stock
25 mg	$218	In stock
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Biological Activity

PNU-22394 hydrochloride is a potent agonist for 5-HT receptors with Ki of 6.1 and 10 nM, EC50 of 7.7 nM and 23 nM for 5-HT2C and 5-HT2A, respectively.

Physicochemical Properties

M.Wt	236.74
Formula	C13H17ClN2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	6-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole hydrochloride

References

1. Ennis MD, et al. Bioorg Med Chem Lett. 2003 Jul 21;13(14):2369-72.

2. ensen AA, et al. J Med Chem. 2013 Feb 14;56(3):1211-27.

3. Arias HR, et al. Eur J Pharmacol. 2026 Jun 10;1026:178918.

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PNU-22394 hydrochloride (PNU22394)

Biological Activity

Physicochemical Properties

References

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