Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : PPBI
Catalog No.: PC-61789Not For Human Use, Lab Use Only.
PPBI is a potent, selective, full M1 muscarinic agonist with EC50 of 5, 8, and 21 nM for human, rat, and mouse M1 receptors, respectively.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
PPBI is a potent, selective, full M1 muscarinic agonist with EC50 of 5, 8, and 21 nM for human, rat, and mouse M1 receptors, respectively.
PPBI displays a functional potency more than 10-fold than that of M4, >100-fold more potent over M2, M3 and M5.
PPBI reverses d-amphetamine locomotor activity, also reverses a natural deficit in a rat cognition model.
PPBI is analgesic in a variety of rat and mouse models.
| M.Wt | 376.432 | |
| Formula | C19H25FN4O3 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Wood MW, et al. Neuropharmacology. 2017 Sep 1;123:233-241.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
