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PQC 083

Chemical Structure : PQC 083

CAS No.: 1563006-38-1

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PQC 083 (PQC083, PQC-083)

Catalog No.: PC-62757Not For Human Use, Lab Use Only.

PQC 083 is a novel nerve growth factor (NGF) antagonist with IC50 of 7.0 uM, functionally inhibits NGF's effects on PC12 cell differentiation.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    PQC 083 is a novel nerve growth factor (NGF) antagonist with IC50 of 7.0 uM, functionally inhibits NGF's effects on PC12 cell differentiation.
    PQC 083 is a useful biochemical tool for studying NGF-dependent effects in biochemical or cell biology systems.

    Physicochemical Properties

    M.Wt 318.249
    Formula C12H10N6O5
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    5,7-diamino-4-methyl-3-nitro-9-oxo-4,9-dihydropyrazolo[5,1-b]quinazoline-2-carboxylic acid

    References

    1. Eibl JK, et al. Eur J Pharmacol. 2013 May 15;708(1-3):30-7.

    2. Sheffield KS, et al. Pharmacol Res. 2016 Jan;103:292-9.

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