PQM-244 | MAO-B inhibitor | Probechem Biochemicals

Chemical Structure : PQM-244

PQM-244 (PQM244)

Catalog No.: PC-25717Not For Human Use, Lab Use Only.

PQM-244 is a selective MAO-B inhibitor with IC50 of 4.17 uM with non-competitive inhibition mechanism (Ki=2.28 uM), shows significant peripheral and central antinociceptive effects.

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Biological Activity

PQM-244 is a selective Monoamine oxidase B (MAO-B) inhibitor with IC50 of 4.17 uM with non-competitive inhibition mechanism (Ki=2.28 uM), shows significant peripheral and central antinociceptive effects.

Physicochemical Properties

M.Wt	298.39
Formula	C18H22N2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S,E)-4-methoxy-N’-(2-methyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-ylidene)benzohydrazide

References

1. Dos Reis Rosa Franco G, et al. Future Med Chem. 2025 Jun;17(11):1229-1240.

2. Dos Reis VEN, et al. J Pharm Biomed Anal. 2025 Oct 15;268:117200.

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PQM-244 (PQM244)

Biological Activity

Physicochemical Properties

References

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